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Thermodynamic investigation of thermoresponsive xanthan‐poly ( N ‐isopropylacrylamide) hydrogels
Author(s) -
Hamcerencu Mihaela,
Desbrieres Jacques,
Khoukh Abdel,
Popa Marcel,
Riess Gérard
Publication year - 2011
Publication title -
polymer international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.592
H-Index - 105
eISSN - 1097-0126
pISSN - 0959-8103
DOI - 10.1002/pi.3113
Subject(s) - lower critical solution temperature , self healing hydrogels , poly(n isopropylacrylamide) , magic angle spinning , materials science , thermoresponsive polymers in chromatography , polymer , differential scanning calorimetry , chemical engineering , interpenetrating polymer network , polymer chemistry , phase transition , phase (matter) , chemistry , copolymer , composite material , thermodynamics , nuclear magnetic resonance spectroscopy , organic chemistry , physics , reversed phase chromatography , engineering
Polysaccharide‐based hydrogels, such as xanthan maleate/poly( N ‐isopropylacrylamide) (PNIPAAm) interpenetrated polymer networks, are thermostimulable materials of interest for the controlled release of biologically active components due to conformation changes at the low critical‐solution temperature (LCST) PNIPAAm phase transition. The phase transition of these interpenetrated polymer network hydrogels, where PNIPAAm is in a ‘confined’ environment, was examined by high resolution magic angle spinning nuclear magnetic resonance and differential scanning calorimetry. High resolution magic angle spinning nuclear magnetic resonance spectroscopy allows the accurate determination of LCST and an evaluation of the corresponding thermodynamic data. More particularly, the evolution of these data as a function of the composition of the hydrogel, and of the external parameters such as pH and ionic strength, was considered. LCST shows a minimal value with increasing xanthan content. Moreover, it was possible to calculate, as a function of temperature, the fraction of NIPAAm which remains uncollapsed. The data obtained for pure PNIPAAm hydrogels are in good agreement with recently published results. The phase transition of PNIPAAm in a diphasic hydrogel is broader when PNIPAAm is ‘confined’ within an interpenetrated polymer network than in a pure PNIPAAm crosslinked network. The widening of the transition with increasing xanthan content indicates a reduction of the PNIPAAm interchain aggregation in a network structure. Copyright © 2011 Society of Chemical Industry