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On the hydrodynamic analysis of conformation in mixed biopolymer systems
Author(s) -
Harding Stephen E,
Abdelhameed Ali S,
Morris Gordon A
Publication year - 2011
Publication title -
polymer international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.592
H-Index - 105
eISSN - 1097-0126
pISSN - 0959-8103
DOI - 10.1002/pi.2934
Subject(s) - biopolymer , flexibility (engineering) , polymer , chemistry , polysaccharide , polymer science , nanotechnology , materials science , mathematics , biochemistry , organic chemistry , statistics
A brief review is given of some of the advances in hydrodynamic methodologies for studying the conformation and flexibility of biomacromolecules in mixed systems. We consider first of all the evaluation of conformation type and flexibility in polymer systems with a quasi‐continuous distribution of molecular weight, using polysaccharides and mucin glycoproteins as our main examples, and then conformation determination in discrete or paucidisperse systems such as aggregated antibody preparations. Copyright © 2010 Society of Chemical Industry