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Dendrimers as drug delivery vehicles: non‐covalent interactions of bioactive compounds with dendrimers
Author(s) -
Crampton Hannah L,
Simanek Eric E
Publication year - 2007
Publication title -
polymer international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.592
H-Index - 105
eISSN - 1097-0126
pISSN - 0959-8103
DOI - 10.1002/pi.2230
Subject(s) - dendrimer , covalent bond , drug delivery , nanotechnology , drug , chemistry , combinatorial chemistry , materials science , pharmacology , organic chemistry , medicine
This mini review highlights issues associated with the use of dendrimers as drug delivery vehicles. The review introduces dendrimers and summarizes findings on their use in vivo and in vitro . Specifically, this review is limited to examples wherein the drug is non‐covalently associated with the dendrimer. Examples wherein the drug is covalently attached to the dendrimer are not discussed. Copyright © 2007 Society of Chemical Industry