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Facile polyester surface functionalization via hydrolysis and cell‐recognizing peptide attachment
Author(s) -
Sun Hui,
Önneby Sara
Publication year - 2006
Publication title -
polymer international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.592
H-Index - 105
eISSN - 1097-0126
pISSN - 0959-8103
DOI - 10.1002/pi.2090
Subject(s) - surface modification , hydrolysis , sodium hydroxide , contact angle , polycaprolactone , polyester , covalent bond , polymer , x ray photoelectron spectroscopy , materials science , hydroxide , alkaline hydrolysis , chemistry , peptide , chemical engineering , polymer chemistry , organic chemistry , composite material , biochemistry , engineering
Facile surface modification of biodegradable polycaprolactone via alkali hydrolysis and subsequent attachment of a cell‐recognizing peptide to the hydrolysed polymer surface is reported. Surface hydrolysis was carried out in sodium hydroxide solution. The modification was studied with regard to hydrolysis time, temperature and alkaline concentration. A cell‐recognizing peptide was covalently attached to the hydrolysed polymer surface. Contact angle measurements, X‐ray photoelectron spectroscopy and ultraviolet spectroscopy were used to characterize the modified surface and to confirm the occurrence of the coupling reaction. Copyright © 2006 Society of Chemical Industry