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Use of Remdesivir in Myasthenia gravis and COVID‐19
Author(s) -
Peters Bradley J.,
Rabinstein Alejandro A.,
DuBrock Hilary M.
Publication year - 2021
Publication title -
pharmacotherapy: the journal of human pharmacology and drug therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.227
H-Index - 109
eISSN - 1875-9114
pISSN - 0277-0008
DOI - 10.1002/phar.2524
Subject(s) - myasthenia gravis , medicine , covid-19 , dexamethasone , coronavirus , respiratory failure , disease , intensive care medicine , immunology , virology , infectious disease (medical specialty) , outbreak
Myasthenia gravis and the associated pharmacologic management options could place patients at higher risk of contracting severe acute respiratory syndrome coronavirus 2 and exhibiting more severe manifestations of the novel coronavirus disease 2019 (COVID‐19). Multiple agents have been studied for the management of the COVID‐19, including remdesivir. To date, no published reports have evaluated the utilization of the antiviral remdesivir in patients with myasthenia gravis. We describe the first reported clinical course of three patients with myasthenia gravis who safely received remdesivir in combination with dexamethasone for the management of COVID‐19.