Premium
A comparison of the collagen triple helix and coiled‐coil peptide building blocks on metal ion‐mediated supramolecular assembly
Author(s) -
Curtis Ryan W.,
Chmielewski Jean
Publication year - 2021
Publication title -
peptide science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.533
H-Index - 7
ISSN - 2475-8817
DOI - 10.1002/pep2.24190
Subject(s) - supramolecular chemistry , coiled coil , peptide , triple helix , metal , helix (gastropod) , nanotechnology , collagen helix , self assembly , chemistry , materials science , crystallography , biochemistry , stereochemistry , biology , crystal structure , ecology , organic chemistry , snail
Metal ion‐mediated assembly of peptides is an intriguing method for developing novel biomaterials. In particular, peptide building blocks based on collagen triple helical and coiled‐coil peptides have been functionalized with metal‐binding ligands and assemble into hierarchical structures with diverse potential applications. This review outlines the use of metal‐mediated assembly with these supramolecular structures and highlights how changes in the building blocks lead to significant differences in structural morphologies, with the identity of the metal‐binding ligands and their placement on the building block as crucial aspects in the bottom‐up development of the assemblies.