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Microspheres and microcapsules, a survey of manufacturing techniques Part II: Coacervation
Author(s) -
Arshady Reza
Publication year - 1990
Publication title -
polymer engineering and science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.503
H-Index - 111
eISSN - 1548-2634
pISSN - 0032-3888
DOI - 10.1002/pen.760301505
Subject(s) - coacervate , gelatin , materials science , microsphere , polymer , chromatography , phase (matter) , aqueous solution , chemical engineering , polymer science , nanotechnology , chemistry , composite material , organic chemistry , engineering
Abstract A methodological survey of coacervation/phase separation techniques employed for the preparation of microspheres and microcapsules is presented. Basic features of macromolecular coacervation are discussed, and a classification of different coacervation procedures (i.e., simple, complex, aqueous, and nonaqueous) is provided. Microsphere formation and microencapsulation techniques based on coacervation/phase separation of gelatin, gelatin‐acacia, and ethylcellulose are described, and those of a wide range of other polysaccharide derivatives and synthetic polymers are tabulated. The dependence of microsphere/microcapsule characteristics on manufacturing parameters and performance evaluation of microspherical/microcapsular products are also discussed.