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Solute diffusion in swollen membranes. Part V: Solute diffusion in poly(2‐hydroxyethyl methacrylate)
Author(s) -
Moynihan Humphrey J.,
Honey Martha S.,
Peppas Nikolaos A.
Publication year - 1986
Publication title -
polymer engineering and science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.503
H-Index - 111
eISSN - 1548-2634
pISSN - 0032-3888
DOI - 10.1002/pen.760261703
Subject(s) - membrane , methacrylate , diffusion , polymer chemistry , materials science , monomer , swelling , ethylene glycol dimethacrylate , ethylene glycol , chemical engineering , polymer , chemistry , composite material , thermodynamics , biochemistry , physics , engineering , methacrylic acid
Studies with phenylalanine diffusing in well‐characterized poly(2‐hydroxyethyl methacrylate) (PHEMA) membranes swollen in water at 37°C were conducted. Films were prepared by reaction of HEMA monomer with the cross‐linking agent ethylene glycol dimethacrylate (EGDMA) at cross‐linking ratios, X, of 0.005, 0.01, 0.0128, 0.025, and 0.050 mole EGDMA/mole HEMA in the presence of 40 weight percent water at 60°C for 12 hours. These membranes were subsequently swollen in water at 37°C and their structure analyzed using a modified Gaussian distribution equation of swelling. The calculated values of M̄ c varied between 1,700 and 3,425 daltons, which corresponded to a correlation length of the mesh size, egr, of 24 to 35 A. The phenylalanine solute diffusion coefficient varied from 0.17 × 10 −6 to 0.97 × 10 −6 cm 2 /s, and depended on the aforementioned structural parameters of the membranes.