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A review on microfabrication of thermoplastic polymer‐based microneedle arrays
Author(s) -
Juster Herwig,
Aar Bart,
Brouwer Hans
Publication year - 2019
Publication title -
polymer engineering and science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.503
H-Index - 111
eISSN - 1548-2634
pISSN - 0032-3888
DOI - 10.1002/pen.25078
Subject(s) - transdermal , materials science , microfabrication , embossing , compounding , molding (decorative) , nanotechnology , thermoplastic , commercialization , polymer , composite material , fabrication , medicine , alternative medicine , pathology , political science , law , pharmacology
This article will provide an overview of recent developments for microneedles made using injection molding and hot embossing techniques for active transdermal drug delivery. Microneedle arrays are developed for pain‐free and efficient drug delivery without using a cold chain. The focus of this article will be on the use of engineering thermoplastics and microneedle manufacturing techniques including patterning. Recent developments demonstrate that commercialization of polymer‐based microneedle systems is feasible. POLYM. ENG. SCI., 59:877–890, 2019. © 2019 Society of Plastics Engineers