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Development of novel porous nasal scaffold using injection molding
Author(s) -
Teng PingTun,
Chern MingJyh,
Shen YungKang,
Chiang YuhChyun
Publication year - 2013
Publication title -
polymer engineering and science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.503
H-Index - 111
eISSN - 1548-2634
pISSN - 0032-3888
DOI - 10.1002/pen.23317
Subject(s) - materials science , scaffold , silicone , biocompatibility , porosity , molding (decorative) , biomedical engineering , tissue engineering , polymer , cartilage , biodegradable polymer , fabrication , composite material , anatomy , medicine , metallurgy , alternative medicine , pathology
Porous scaffolds fabricated from biodegradable polymers have been widely used and play a vital role in tissue engineering and in situ tissue reconstruction. This study presents a novel fabrication technique involving injection molding and conventional particulate leaching (IM/PL) to obtain the L‐shaped nasal scaffold for rhinoplasty. The results indicate that the porous nasal scaffold made by the IM/PL method shows the acceptable biocompatibility and degradation. The nasal scaffold may degrade well after surgery and the cartilage tissue may grow well in it. This IM/PL technique may replace the traditional artificial silicone filler and reduce the surgery cost. POLYM. ENG. SCI. 2013. © 2012 Society of Plastics Engineers