Open AccessClinical research study designs: The essentials
Author(s) -
Chidambaram Ambika G.,
Josephson Maureen
Publication year - 2019
Publication title -
pediatric investigation
Language(s) - English
Resource type - Journals
ISSN - 2574-2272
DOI - 10.1002/ped4.12166
Subject(s) - harm , management science , foundation (evidence) , research design , clinical study design , clinical research , computer science , engineering ethics , health care , basic research , clinical trial , medicine , psychology , engineering , social psychology , sociology , social science , political science , pathology , library science , law
In clinical research, our aim is to design a study which would be able to derive a valid and meaningful scientific conclusion using appropriate statistical methods. The conclusions derived from a research study can either improve health care or result in inadvertent harm to patients. Hence, this requires a well‐designed clinical research study that rests on a strong foundation of a detailed methodology and governed by ethical clinical principles. The purpose of this review is to provide the readers an overview of the basic study designs and its applicability in clinical research.