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Antibiotic use profile at paediatric clinics in two transitional countries
Author(s) -
Palčevski Goran,
Ahel Vladimir,
VlahovićPalčevski Vera,
Ratchina Svetlana,
RosovicBazijanac Vesna,
Averchenkova L.
Publication year - 2004
Publication title -
pharmacoepidemiology and drug safety
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.023
H-Index - 96
eISSN - 1099-1557
pISSN - 1053-8569
DOI - 10.1002/pds.880
Subject(s) - medicine , antibiotics , amoxicillin , cefuroxime , defined daily dose , pharmacoepidemiology , pediatrics , gentamicin , ceftriaxone , drug , pharmacology , microbiology and biotechnology , medical prescription , biology
Purpose In this study, we evaluated antibiotic utilisation pattern at two paediatric clinics in different European (transitional) countries: Croatia (Rijeka) and Russia (Smolensk). Methods Antibiotic utilisation during the year 2000 was observed using the ATC/defined daily doses (DDD) methodology (ATC code‐J01). Drug‐usage data was expressed in numbers of DDD/100 bed‐days and the DU90% profile. Results In Rijeka, 35 different systemic antibiotics were used and in Smolensk 22. The overall consumption of antibiotic drugs in Rijeka was more than three times higher than in Smolensk (28.96 vs 8.3 DDD/100 bed‐days). The top five antibiotic drugs used in Smolensk were amoxicillin, mydecamicin, ampicilin, doxycylin, gentamicin; and in Rijeka cefuroxime axetil, ceftriaxone, azytromycin, ceftibuten and amoxicillin. Conclusion Differences in antibiotic prescribing patterns are greater than expected. The pattern of antibiotic utilisation in both countries implies that regional control measures and guidelines for antibiotic use in children should be urgently established. Copyright © 2003 John Wiley & Sons, Ltd.