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Short‐term effects of heat and cold on respiratory drug use. A time‐series epidemiological study in A Coruña, Spain
Author(s) -
Royé Dominic,
Figueiras Adolfo,
Taracido Margarita
Publication year - 2018
Publication title -
pharmacoepidemiology and drug safety
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.023
H-Index - 96
eISSN - 1099-1557
pISSN - 1053-8569
DOI - 10.1002/pds.4427
Subject(s) - medicine , pharmacoepidemiology , epidemiology , drug , environmental health , distributed lag , psychological intervention , respiratory system , public health , multimorbidity , outbreak , term (time) , statistics , pharmacology , medical prescription , population , mathematics , virology , physics , nursing , quantum mechanics , psychiatry
Abstract The consumption of medication, especially over‐the‐counter drugs, can reflect environmental exposure with a lesser degree of severity in terms of morbidity. The non‐linear effects of maximum and minimum apparent temperature on respiratory drug sales in A Coruña from 2006 to 2010 were examined using a distributed lag nonlinear model. In particular, low apparent temperatures proved to be associated with increased sales of respiratory drugs. The strongest consistent risk estimates were found for minimum apparent temperatures in respiratory drug sales with an increase of 33.4% (95% CI, 12.5%‐58.0%) when the temperature changed from 2.8°C to −1.4 °C. These findings may serve to guide the planning of public health interventions to predict and manage the health effects of exposure to the thermal environment for lower degrees of morbidity. More precisely, significant increases in the use of measured over‐the‐counter medication could be used to identify and anticipate influenza outbreaks due to a more sensitive degree of the data source.