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The determinants of warfarin requirements in Chinese patients
Author(s) -
Chan Thomas Y. K.,
Tsoi W. C.,
Critchley Julian A. J. H.
Publication year - 1992
Publication title -
pharmacoepidemiology and drug safety
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.023
H-Index - 96
eISSN - 1099-1557
pISSN - 1053-8569
DOI - 10.1002/pds.2630010510
Subject(s) - medicine , warfarin , deep vein , thrombosis , pharmacoepidemiology , body weight , anesthesia , pharmacology , atrial fibrillation , medical prescription
The warfarin requirements of 33 Chinese patients presenting with deep vein thrombosis and/or pulmonary thromboembolism were studied. The mean daily maintenance dosage was considerably lower in Chinese (3 mg) than in Caucasian subjects (4–6 mg) and, as in Caucasian subjects, the age of the patient rather than body weight was an important determinant of warfarin requirements ( r = 0.4, p < 0.05).