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Age and the spontaneous reporting of adverse reactions in the United Kingdom
Author(s) -
Mann R. D.,
Rawlins M. D.,
Fletcher P.,
Wood S. M.
Publication year - 1992
Publication title -
pharmacoepidemiology and drug safety
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.023
H-Index - 96
eISSN - 1099-1557
pISSN - 1053-8569
DOI - 10.1002/pds.2630010105
Subject(s) - medicine , medical prescription , demography , pharmacoepidemiology , population , pediatrics , environmental health , pharmacology , sociology
A study designed to investigate the relationship between age, spontaneous ADR reporting rates, general practice prescription volumes and population sizes has shown that, in the UK, from age 15 years and above, greater numbers of prescriptions are issued for females than for males; the sex difference in prescribing rates is most marked in respect of women during their reproductive years. ADR reporting rates are also much affected by age and, in respect of all ADRs, are highest in the fifth and sixth decades but appear to decline thereafter. Reporting rates of serious ADRs show a similar, though less pronounced trend, and again appear to decline in the ninth decade.