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Risks of herbal medicinal products
Author(s) -
Ernst E.
Publication year - 2004
Publication title -
pharmacoepidemiology and drug safety
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.023
H-Index - 96
eISSN - 1099-1557
pISSN - 1053-8569
DOI - 10.1002/pds.1014
Subject(s) - narrative review , medicine , popularity , medical prescription , risk analysis (engineering) , consumer safety , traditional medicine , pharmacology , intensive care medicine , psychology , social psychology
Purpose Herbal medicinal products (HMPs) are again highly popular. Their current popularity renders the assessment of their safety an urgent necessity. Method Narrative review using examples only. Results Constituents of HMPs can be toxic and numerous examples of liver, kidney or other organ damage are on record. All HMPs contain a range of pharmacologically active constituents, and users of HMPs often combine HMPs with prescribed drugs. Thus herb–drug interactions are a real possibility. In most countries, HMPs are not submitted to stringent regulation and control. Thus unreliable quality can be a problem. In particular, this poses a risk when HMPs are contaminated (e.g. with heavy metals) or adulterated (e.g. with prescription drugs). The medical literature holds numerous examples for all of these scenarios and some are used in this article to illustrate the above points. As this area is grossly under‐researched, it is rarely possible to define the size of the problem. Conclusions It is concluded that the widespread notion of HMPs being inherently safe is naïve at best and dangerous at worst. More research is required to minimise the risk HMPs may pose to consumers' health. Copyright © 2004 John Wiley & Sons, Ltd.