Premium
Mild pyelectasis: evaluating the relationship between gestational age and renal pelvic anterior–posterior diameter
Author(s) -
Odibo Anthony O.,
Marchiano Dominic,
Quis Joanne N.,
Riesch Deborah,
Egan Jim F. X.,
Macones George A.
Publication year - 2003
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.709
Subject(s) - gestational age , medicine , gestation , obstetrics , renal function , urology , pregnancy , biology , genetics
Objective To determine the relationship between gestational age and renal pelvic anterior–posterior diameter and the feasibility of developing gestational age–specific thresholds for the diagnosis of mild pyelectasis. Methods Cross‐sectional study of 420 singleton fetuses between 16 and 39 weeks' gestation. The mean renal AP diameter as a function of gestational age was determined using fractional polynomial regression models and centile plots were generated. Assessment of goodness of fit for each regression model was performed. Results There was a positive correlation between gestational age and renal pelvic AP diameter (Pearson's Correlation Coefficient 0.65). Using the derived mean and standard deviations of renal AP diameter, gestational‐age specific 95% reference levels were generated. The sensitivity, specificity, positive, and negative predictive values of using the gestational age‐specific cutoffs for predicting persistent postnatal renal anomaly were 80%; 99%; 29%; and 99% respectively. Conclusion There is a positive correlation between gestational age and renal pelvic AP diameters. Reliable gestational age‐specific renal AP thresholds for diagnosis of pyelectasis are provided. Copyright © 2003 John Wiley & Sons, Ltd.