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Outcomes of hypoplastic left heart syndrome and fetal aortic valvuloplasty in a country with suboptimal postnatal management
Author(s) -
CruzLemini Mónica,
AlvaradoGuaman Monica,
NietoCastro Belen,
LunaGarcia Jonathan,
MartínezRodríguez Miguel,
JuarezMartínez Israel,
PalaciosMacedo Alexis,
CruzMartínez Rogelio
Publication year - 2019
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.5470
Subject(s) - hypoplastic left heart syndrome , medicine , fetus , cardiology , aortic valvuloplasty , pregnancy , aortic valve , heart disease , aortic valve stenosis , biology , genetics
What is already known about this topic? Fetal aortic valvuloplasty may prevent progression to hypoplastic left heart syndrome (HLHS) in utero and, thus, decrease postnatal morbidity Despite the high survival rate of HLHS in developed countries, many studies suggest that the risks of this fetal intervention may outweigh the benefits. What does this study add? Fetal aortic valvuloplasty is associated with ≈50% long‐term survival, while HLHS currently carries more than 95% risk of perinatal death in countries with suboptimal postnatal management, with little or no experience regarding surgical palliation, and with the vast majority of cases receiving comfort measures.