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Novel usage of microfocus computed tomography (micro‐ CT ) for visualisation of human embryonic development— I mplications for future non‐invasive post‐mortem investigation
Author(s) -
Shelmerdine Susan Cheng,
Hutchinson John Ciaran,
Kang Xin,
Suich Joseph D.,
Ashworth Michael,
Cannie Mieke M.,
Segers Valerie,
Sebire Neil J.,
Jani Jacques C.,
Arthurs Owen J.
Publication year - 2018
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.5281
Subject(s) - fetus , embryo , gestation , embryogenesis , computed tomography , pathological , autopsy , gestational age , pathology , medicine , embryonic stem cell , radiology , biology , pregnancy , microbiology and biotechnology , genetics , gene , biochemistry
What's already known about this topic? Accurate pathological assessment of small gestational age fetuses is challenging. Dating an embryo/fetus is essential to recognise expected human developmental stages and prevent misdiagnosis.What does this study add? Micro‐CT offers a non‐destructive, digital method for dating human embryos. The micro‐CT imaging here is of the earliest gestation human embryo published to date with corresponding pathology. It can provide an alternative to autopsy even at early stages of development.