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Amniocentesis for prenatal diagnosis of cytomegalovirus infection: challenging the 21 weeks' threshold
Author(s) -
Enders M.,
Daiminger A.,
Exler S.,
Enders G.
Publication year - 2017
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.5107
Subject(s) - amniocentesis , gestation , obstetrics , medicine , cytomegalovirus , prenatal diagnosis , pregnancy , cytomegalovirus infections , gynecology , fetus , herpesviridae , viral disease , human cytomegalovirus , immunology , virus , biology , genetics
What's already known about this topic? Current guidelines recommend performing amniocentesis for prenatal diagnosis of CMV infection not before 21 weeks' gestation and at least 6 weeks after maternal infection. What does this study add? Our data suggest that amniocentesis can be done before 21 weeks' gestation without significant loss of sensitivity. This has to be confirmed in a controlled study. © 2017 John Wiley & Sons, Ltd.