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A genotype–phenotype correlation study reveals that a non‐coding RNA might be associated with cardiovascular anomalies in fetuses with WHS
Author(s) -
Wu Yi,
Tao Jiong,
Wang YanLin,
Hu WenJing,
Han Xu,
Cheng WeiWei
Publication year - 2016
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.4884
Subject(s) - phenotype , genotype , genetics , biology , genotype phenotype distinction , fetus , correlation , chromosome , gene , pregnancy , geometry , mathematics
What's Already Known About This Topic? Wolf–Hirschhorn syndrome is a genetic disorder caused by partial deletion of the short arm of chromosome It consists of a broad spectrum of clinical manifestations. The deletion size also varies significantly.What Does This Study Add? This study found that a non‐coding RNA (NR_130734) might be involved in cardiovascular development by analyzing the genotype–phenotype correlation of two fetuses with Wolf–Hirschhorn syndrome.