Premium
Factors associated with fetal shunt dislodgement in lower urinary tract obstruction
Author(s) -
Kurtz Michael P.,
Koh Chester J.,
Jamail Grace Anne,
SangiHaghpeykar Haleh,
Shamshirsaz Alireza A.,
Espinoza Jimmy,
Cass Darrell L.,
Olutoye Oluyinka O.,
Olutoye Olutoyin A.,
Braun Michael C.,
Roth David R.,
Belfort Michael A.,
Ruano Rodrigo
Publication year - 2016
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.4850
Subject(s) - medicine , fetus , shunt (medical) , gestational age , urinary tract obstruction , surgery , urinary system , pregnancy , genetics , biology
Objective To identify factors associated with fetal shunt dislodgement in lower urinary tract obstruction (LUTO). Methods We conducted a retrospective study of 42 consecutive fetuses with a diagnosis of LUTO in a tertiary fetal center between April 2013 and November 2015. Possible factors associated with prenatal shunt dislodgment were evaluated in fetuses who underwent shunt placement, including gestational age at diagnosis, gestational age at procedure, presence of ‘keyhole sign’, initial fetal bladder volume and wall thickness, prenatal ultrasonographic renal characteristics, amniotic fluid volume, presence of ascites prior to shunting, and type of fetal shunt. Results Nineteen (46.3%) fetuses underwent shunt placement at a median gestational age of 19 (range: 16.3–31.1) weeks. Shunt dislodgement occurred in 10 (52.6%) patients. A total of 35 procedures were performed; among which 16 (45.7%) were repeat procedures. The only prenatal factor associated with shunt dislodgement was the type of the shunt; Kaplan–Meier analysis indicated that the Rocket was associated with increased likelihood of remaining orthotopic ( p = 0.04). Conclusion Fetal shunt dislodgement occurs in approximately half of the patients and appears to be associated with the type of the shunt. Future research is necessary to develop better shunt systems and to investigate different fetal therapeutic approaches. © 2016 John Wiley & Sons, Ltd.