Premium
Fetal capillary haemangioblastoma: an exceptional tumour. A review of the literature
Author(s) -
Diguet Alain,
Laquerrière Annie,
Eurin Danielle,
ChanavazLacheray Isabella,
Magdeleine Ruchoux Marie,
Rossi Annick,
Marpeau Loïc
Publication year - 2002
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.452
Subject(s) - cerebellopontine angle , pathology , fetus , medicine , autopsy , cerebellum , anatomy , radiology , pregnancy , biology , magnetic resonance imaging , genetics , endocrinology
We report a case of a fetal haemangioblastoma located in the cerebellopontine angle. On prenatal ultrasonographic examination a hyperechogenic and heterogeneous mass with a major vascularization on colour Doppler imaging was observed. It increased progressively and laminated the cerebellum. A neoplastic tumour was suspected but its extent into the cerebral peduncle was unclear. Diagnosis was made at autopsy using histological, immunohistochemical and flow cytometric evaluation. Haemangioblastoma is an exceptional congenital tumour, which is either sporadic or integrated in von Hippel‐Lindau disease (VHLD). We discuss the obstetrical management of prenatal brain tumours and the genetic counselling of haemangioblastoma. Copyright © 2002 John Wiley & Sons, Ltd.