Premium
Prenatal characteristics of false negative cases from first‐trimester screening of Down syndrome (trisomy 21)
Author(s) -
Simonsen Tanja Schlaikjær,
Sørensen Steen,
Ekelund Charlotte,
Jørgensen Finn Stener
Publication year - 2013
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.4081
Subject(s) - trisomy , down syndrome , obstetrics , medicine , crown rump length , nuchal translucency , aneuploidy , gynecology , prenatal diagnosis , first trimester , second trimester , prenatal screening , pregnancy , pregnancy associated plasma protein a , fetus , biology , chromosome , genetics , psychiatry , gene
What's already known about this topic? In DS cases, maternal age, NT and hCGβ (multiples of median) are high, whereas PAPP‐A (multiples of median) is low.What does this study add? This study describes in details the distribution of maternal age, NT, crown rump length and biochemical markers of false negative cases from the first‐trimester combined screening for DS.