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Prenatal identification of esophageal atresia: the role of ultrasonography for evaluation of functional anatomy
Author(s) -
Shulman Adrian,
Mazkereth Rami,
Zalel Yaron,
Kuint Jacob,
Lipitz Shlomo,
Avigad Itamar,
Achiron Reuwen
Publication year - 2002
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.375
Subject(s) - atresia , ultrasonography , anatomy , identification (biology) , medicine , prenatal diagnosis , prenatal ultrasound , radiology , pathology , fetus , pregnancy , biology , genetics , botany
Objective To suggest a new ultrasonographic approach for prenatal diagnosis of esophageal atresia (EA). Methods Since 1995, whenever EA is suspected, we perform a systematic multiplanar ultrasonographic scanning of the fetal upper body in order to demonstrate an esophageal pouch. This includes three image plans of the neck and upper chest: coronal, sagittal and axial views in the cephalic direction. The scan time is 20–30 min. Results Twenty‐five pregnant patients were referred during the period under study for prenatal examinations due to polyhydramnios and/or absent or small stomach. In six fetuses an esophageal pouch was demonstrated at ultrasonography in utero , thus a definitive diagnosis of EA was obtained. All six were confirmed with EA postpartum. In 19 fetuses an esophageal pouch was not demonstrated and all delivered normal neonates. During the same period two additional newborns, who were not included in the referred patients because amniotic fluid volume and stomach size were normal, were diagnosed postpartum with EA. The earliest gestational age of pouch visualization was at 23 weeks. The sagittal view was the best for visualizing a low‐level pouch, and the coronal view was optimal for revealing a high pouch. Conclusions Our three‐sectional view of the neck and upper chest is useful for in utero detection of esophageal pouch that may enhance the prenatal diagnosis of EA. The positive predictive value for prenatal ultrasound for detecting EA is 100% with a sensitivity of 80%. Copyright © 2002 John Wiley & Sons, Ltd.