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Intraventricular haemorrhage in a fetus with cerebral cytomegalovirus infection
Author(s) -
Nigro Giovanni,
La Torre Renato,
Sali Eleonora,
Auteri Maura,
Mazzocco Manuela,
Maranghi Luca,
Cosmi Erich
Publication year - 2002
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.366
Subject(s) - cytomegalovirus , fetus , medicine , gestation , cytomegalovirus infection , betaherpesvirinae , oligohydramnios , herpesviridae , immunology , human cytomegalovirus , virus , pregnancy , virology , viral disease , pathology , biology , genetics
Cytomegalovirus (CMV) is the leading infectious cause of prenatal neurological damage, which is particularly severe when primary maternal infection occurs during the first 16 weeks of gestation, at the time of organ development and neuronal migration. Vascular involvement has been suggested to be among thepossible pathogenic mechanisms of virus‐induced pathology, in addition to direct viral effects. We report on a fetus with cerebral CMV infection, which had intraventricular haemorrhage, together with oligohydramnios and hyperechogenic bowel, following maternal primary CMV infection. Copyright © 2002 John Wiley & Sons, Ltd.