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Prenatal diagnosis of partial agenesis of the corpus callosum in a fetus with thanatophoric dysplasia type 2
Author(s) -
Kalache Karim D.,
Lehmann Katarina,
Chaoui Rabih,
Kivelitz Dietmar E.,
Mundlos Stefan,
Bollmann Rainer
Publication year - 2002
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.327
Subject(s) - agenesis of the corpus callosum , corpus callosum , fetus , dysplasia , medicine , magnetic resonance imaging , agenesis , anatomy , prenatal diagnosis , pathology , radiology , pregnancy , biology , genetics
A fetus with thanatophoric dysplasia type 2 (TD2) associated with cloverleaf skull and abnormal development of the corpus callosum is reported. This case represents the first prenatal direct visualization of a partial agenesis of the corpus callosum (ACC) using high‐resolution ultrasonography and colour power Doppler, which was confirmed by post‐mortem magnetic resonance imaging (MRI). The causal link between cloverleaf skull in TD and partial ACC is discussed. Copyright © 2002 John Wiley & Sons, Ltd.