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Prenatal diagnosis of cerebral lesions acquired in utero and with a late appearance
Author(s) -
Carletti Angela,
Colleoni Giulia Gandolfi,
Perolo Antonella,
Simonazzi Giuliana,
Ghi Tullio,
Rizzo Nicola,
Pilu Gianluigi
Publication year - 2009
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.2244
Subject(s) - medicine , in utero , prenatal diagnosis , magnetic resonance imaging , pregnancy , fetus , radiology , pediatrics , genetics , biology
Although no precise figures are available, many congenital brain lesions arise from intrauterine disruption, frequently due to obstetric complications. The most common entities include intracranial hemorrhage, ischemic lesions, thrombosis of venous vessels and infections. Accurate prenatal diagnosis is possible in many of these cases. However, the findings may be subtle, particularly in the early stage of the disruptive process. Identification of these conditions requires therefore specific expertise, the combination of fetal neurosonography and magnetic resonance, and frequently there is a need for serial examinations. Targeted diagnostic imaging should be offered to obstetric patients with conditions predisposing to prenatal cerebral insults. Copyright © 2009 John Wiley & Sons, Ltd.