Premium
Trisomy 16 fetus surviving into the second trimester
Author(s) -
Cusick William,
Bork Michael,
Fabri Betsy,
Benn Peter,
Rodis John F.,
Buttino Louis
Publication year - 1995
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1970151115
Subject(s) - trisomy , fetus , medicine , hypoplasia , obstetrics , gestation , prenatal diagnosis , pregnancy , karyotype , aneuploidy , gynecology , surgery , chromosome , biology , genetics , gene
A 27‐year‐old gravida 4, para 3 was found to have anhydramnios at 14 weeks' gestation following a size/date discrepancy noted at her routine prenatal visit. A detailed ultrasound revealed multiple fetal anomalies including congenital heart defect, chest hypoplasia, and bilateral dysplastic kidneys. Karyotype revealed trisomy 16 in 15/15 cells from a tissue specimen obtained from the fetal cord insertion site following elective pregnancy termination.