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Prenatal diagnosis of twin zygosity by DNA ‘fingerprint’ analysis
Author(s) -
Appelman Z.,
Manor M.,
Magal N.,
Caspi B.,
Shohat M.,
Blickstein I.
Publication year - 1994
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1970140412
Subject(s) - zygosity , oligohydramnios , obstetrics , prenatal diagnosis , fetus , twin pregnancy , medicine , fingerprint (computing) , pregnancy , dna profiling , gynecology , biology , dna , genetics , computer science , computer security
Abstract A twin pregnancy with one hydrocephalic fetus with oligohydramnios is presented. Sonographic evaluation could not exclude monochorionicity. Before considering selective feticide, blood samples from both fetuses were examined for DNA ‘fingerprint’ analysis. The different banding patterns of the blood samples established dizygosity. This procedure is suggested in cases where sonography fails to determine chorionicity.