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Prenatal exclusion of duchenne muscular dystrophy by fetal muscle biopsy
Author(s) -
Benzie R. J.,
Ray P.,
Thompson D.,
Hunter A. G. W.,
Iwey B.,
Salvador L.
Publication year - 1994
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1970140402
Subject(s) - duchenne muscular dystrophy , medicine , fetus , muscle biopsy , prenatal diagnosis , muscular dystrophy , obstetrics , biopsy , pregnancy , pediatrics , pathology , biology , genetics
A fetal thigh muscle biopsy was performed at 18 weeks and 6 days' gestation using an automatic 18‐gauge biopsy needle. A positive immunoreaction with antisera to the amino‐ and carboxy‐terminals of dystrophin excluded Duchenne muscular dystrophy from this at‐risk male.