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The association between ‘faint‐positive’ amniotic fluid acetylcholinesterase and fetal malformations
Author(s) -
Sadovsky Yoel,
Robbin Michelle L.,
Crandall Barbara F.,
Filly Roy A.,
Golbus Mitchell S.
Publication year - 1993
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1970131113
Subject(s) - gastroschisis , amniotic fluid , fetus , gestation , acetylcholinesterase , medicine , obstetrics , congenital malformations , prenatal diagnosis , pregnancy , biology , genetics , biochemistry , enzyme
The finding of a ‘faint‐positive’ acetylcholinesterase band in amniotic fluid samples of women at 15 weeks' gestation or above is associated with an increased risk of fetal abnormalities, most commonly gastroschisis. This finding warrants a targeted sonographic evaluation, in order to rule out significant fetal malformations.