The association between ‘faint‐positive’ amniotic fluid acetylcholinesterase and fetal malformations | Zendy

Sadovsky Yoel | Zendy; Robbin Michelle L. | Zendy; Crandall Barbara F. | Zendy; Filly Roy A. | Zendy; Golbus Mitchell S. | Zendy

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The association between ‘faint‐positive’ amniotic fluid acetylcholinesterase and fetal malformations

Author(s) -

Sadovsky Yoel,

Robbin Michelle L.,

Crandall Barbara F.,

Filly Roy A.,

Golbus Mitchell S.

Publication year - 1993

Publication title -

prenatal diagnosis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.956

H-Index - 97

eISSN - 1097-0223

pISSN - 0197-3851

DOI - 10.1002/pd.1970131113

Subject(s) - gastroschisis , amniotic fluid , fetus , gestation , acetylcholinesterase , medicine , obstetrics , congenital malformations , prenatal diagnosis , pregnancy , biology , genetics , biochemistry , enzyme

The finding of a ‘faint‐positive’ acetylcholinesterase band in amniotic fluid samples of women at 15 weeks' gestation or above is associated with an increased risk of fetal abnormalities, most commonly gastroschisis. This finding warrants a targeted sonographic evaluation, in order to rule out significant fetal malformations.

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