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An association between fetal abdominal wall defects and elevated levels of human chorionic gonadotropin in mid‐trimester
Author(s) -
Schmidt D.,
Rose E.,
Greenberg F.
Publication year - 1993
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1970130103
Subject(s) - human chorionic gonadotropin , fetus , medicine , gonadotropin , abdominal wall , pregnancy , obstetrics , second trimester , endocrinology , abdominal wall defect , andrology , gynecology , biology , hormone , anatomy , genetics
We analysed maternal serum human chorionic gonadotropin (hCG) in 16 pregnancies with fetal abdominal wall defects previously identified prenatally by elevated maternal serum alpha‐fetoprotein (AFP) or at birth. The AFP levels had a mean of 6·38 MOM (range 0·34–15·65), as expected with these defects. The hCG levels had a mean of 1·82 MOM (range 0·23–4·11). The hCG levels in five pregnancies (31·25 per cent) were above 2·30 MOM. Elevated levels of hCG may be associated with fetal abdominal wall defects.