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A rare case of a false‐negative finding in both direct and culture of a chorionic villus sample
Author(s) -
Pindar Lesley,
Whitehouse Melanie,
Ocraft Kevin
Publication year - 1992
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1970120607
Subject(s) - chorionic villi , chorionic villus sampling , karyotype , biopsy , fetus , medicine , obstetrics , prenatal diagnosis , gynecology , pregnancy , pathology , andrology , biology , genetics , chromosome , gene
A discrepancy is reported between the karyotype of both direct and cultured chorionic villus cells (46,XX) and a fetal skin biopsy (47,XX,+18). The significance of this result is discussed and compared with similar discordant findings reported in the literature.