Premium
High levels of maternal serum alpha‐fetoprotein and human chorionic gonadotrophins leading to the diagnosis of combined neural tube defect and partial mole
Author(s) -
Zalel Y.,
Weiner E.,
Zabari A.,
Shalev E.
Publication year - 1992
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1970120411
Subject(s) - anencephaly , neural tube , partial hydatidiform mole , mole , alpha fetoprotein , omphalocele , neural tube defect , alpha (finance) , second trimester , endocrinology , medicine , pregnancy , chemistry , biology , gestation , fetus , placenta , embryo , surgery , genetics , construct validity , hepatocellular carcinoma , patient satisfaction
Abstract A case of combined partial mole and neural tube defect is presented. The detection of high levels of both maternal serum (MS) alpha‐fetoprotein (AFP) and human chorionic gonadotrophin (hCG) during the second trimester led to the ultrasonic demonstration of anencephaly, omphalocele, and partial mole. This is the first report of combined elevation of MSAFP and MShCG.