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Blood chemistry of human fetuses in the second and third trimesters
Author(s) -
Legras B.,
Clerc C.,
Ruelland A.,
Vialard J.,
Millon J.,
Cloarec L.
Publication year - 1990
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1970101207
Subject(s) - fetus , alkaline phosphatase , lactate dehydrogenase , endocrinology , medicine , pregnancy , creatinine , pathological , chemistry , enzyme , biology , biochemistry , genetics
Six biochemical parameters and four enzyme activities were determined from the serum of 76 healthy and 56 pathological human fetuses between the 20th and 38th week of pregnancy. In the normal fetuses studied within that period, creatinine, immunoglobulin M, lactate dehydrogenase, and gamma‐glutamyltransferase increased; haemoglobin F and glucose progressively decreased; and alkaline phosphatase was at a peak around the 26th week; cholesterol and triglycerides were always low. The same parameters were also measured in some of the pathological fetuses and compared with their normal counterparts.