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Fetal cystic hygromata: Insights gained from fetal blood sampling
Author(s) -
Tannirandorn Yuen,
Nicolini Umberto,
Nicolaidis Peter C.,
Fisk Nicholas M.,
Arulkumaran Sabaratnam,
Rodeck Charles H.
Publication year - 1990
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1970100309
Subject(s) - cystic hygroma , fetus , trisomy , prenatal diagnosis , aneuploidy , obstetrics , medicine , karyotype , pregnancy , monosomy , gynecology , biology , genetics , chromosome , gene
Twelve second‐trimester fetuses with cystic hygroma underwent fetal blood sampling for rapid karyotyping, haematologic evaluation, and blood gas analysis. An abnormal karyotype was found in seven cases: monosomy X in five, trisomy 21 in one, and trisomy 13 in the other. Eight often fetuses undergoing blood gas analysis showed hypoxaemia, five of which were growth‐retarded. Nine pregnancies were terminated. Of the remaining three, only one fetus survived the perinatal period.