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Transabdominal chorionic villus sampling in the second trimester of pregnancy: Feto‐maternal transfusions in relation to pregnancy outcome
Author(s) -
Los F. J.,
Pijpers L.,
Jahoda M. G. J.,
Sachs E. S.,
Reuss A.,
Hagenaars A. M.,
Wladimiroff J. W.
Publication year - 1989
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1970090711
Subject(s) - chorionic villus sampling , medicine , obstetrics , pregnancy , hydrops fetalis , chorionic villi , gynecology , fetus , first trimester , prenatal diagnosis , biology , genetics
Abstract Volumes of feto‐maternal transfusions (FMTs) in transabdominal chorionic villus sampling (TACVS) in the second trimester of pregnancy were calculated from the difference between maternal alpha‐fetoprotein (AFP) concentrations before and 1 h after TACVS. In 50 pregnancies, there existed no correlation between FMT volume and the amount of villi collected or the number of TACVS attempts. The expected risk of fetal exsanguination due to very voluminous FMT could not be substantiated. In one case, immunization could have been the cause of hydrops fetalis, although only a volume of 0.15 ml could be calculated.