Premium
The use of gamma glutamyl transferase activity in amniotic fluid in the detection of fetal trisomy 21
Author(s) -
Jones S. R.,
Evans S. E.
Publication year - 1988
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1970080109
Subject(s) - trisomy , amniotic fluid , fetus , down syndrome , karyotype , aneuploidy , prenatal diagnosis , obstetrics , medicine , transferase , andrology , chromosome , pregnancy , biology , genetics , biochemistry , enzyme , gene
The value of using gamma glutamyl transferase (GT) to select amniotic fluids for karyotyping from patients at low risk of chromosome defects is assessed. This paper reports on 16 pregnancies with fetal trisomy 21 and compares these to two previous reports of GT in fetal trisomy 21. The value of GT is contrasted to the value of AFP in selecting liquors for karyotyping.