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Prenatal diagnosis of thalidomide syndrome
Author(s) -
Gollop T. R.,
Eigier A.,
Neto J. Guidugli
Publication year - 1987
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1970070411
Subject(s) - thalidomide , medicine , prenatal diagnosis , pediatrics , pregnancy , obstetrics , fetus , biology , genetics , multiple myeloma
A case of thalidomide syndrome diagnosed by ultrasound in the 17th week of pregnancy is presented. The pregnant woman had leprosy and received adjuvant treatment with thalidomide. The affected fetus was exposed to the drug until the 35th day of pregnancy and presented absent external ears, upper limb phocomelia and absent tibiae and fibulae. No internal organ abnormalities were noticed at autopsy.