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Abnormal karyotype in the chorion, not confirmed in a subsequently aborted fetus
Author(s) -
Breed A.,
Mantingh A.,
Govaerts L.,
Boogert A.,
Anders G.,
Laurini R.
Publication year - 1986
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1970060506
Subject(s) - karyotype , chorionic villi , fetus , aborted fetus , biopsy , abortion , aneuploidy , biology , chorionic villus sampling , chromosome abnormality , andrology , chromosome , pathology , gynecology , prenatal diagnosis , medicine , pregnancy , genetics , gene
An abnormal fetal karyotype, containing a del 16(q21‐qter) as an extra chromosome, was diagnosed in all 14 metaphases examined in a sample of chorionic villous biopsy material. After elective abortion a mosaicism for this cell‐line together with a normal one was detected in the chorionic tissue. Fibroblast cultures from several fetal skin biopsies all revealed a normal karyotype.