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Prenatal diagnosis of hunter syndrome using chorionic villi
Author(s) -
Pan N.,
Gatti R.,
Lombardo C.,
Di Natale P.
Publication year - 1986
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1970060307
Subject(s) - chorionic villi , chorionic villus sampling , prenatal diagnosis , hunter syndrome , pregnancy , fetus , biopsy , medicine , obstetrics , gynecology , biology , pathology , genetics
Abstract A case of the Hunter syndrome diagnosed prenatally using chorionic villi is presented. Chorion biopsy was performed in the 10th week of pregnancy. The sample was examined for karyotype and for iduronate sulfatase activity. The fetus was male and the enzyme activity reduced to 4 per cent of normal. Termination of pregnancy occurred at the 11th week.