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Normal blood cell values in the early mid‐trimester fetus
Author(s) -
Millar D. S.,
Davis L. R.,
Rodeck C. H.,
Nicolaides K. H.,
Mibashan R. S.
Publication year - 1985
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1970050602
Subject(s) - fetoscopy , fetus , medicine , gestational age , gestation , obstetrics , prenatal diagnosis , pregnancy , blood sampling , blood cell , biology , genetics
Abstract Samples of pure fetal blood from 116 fetuses of 15–21 weeks' gestation were obtained by direct vision fetoscopy. Ninety nine of these fetuses, presumed to be haematologically normal, were suitable for analysis. The data obtained show that the erythropoietic system is evolving rapidly in this gestational age range. The myeloid series shows no significant increase or decrease in numbers apart from eosinophils and basophils which increase significantly with gestational age whereas the platelet count remains constant. The growing application of fetoscopic blood sampling to the prenatal diagnosis and management of fetal blood disorders renders mandatory a knowledge of normal fetal blood values.