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A case of partial sirenomelia and possible vitamin A teratogenesis
Author(s) -
Von Lennep E.,
El Khazen N.,
De Pierreux G.,
Amy J. J.,
Rodesch F.,
Van Regemorter N.
Publication year - 1985
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1970050107
Subject(s) - pregnancy , vitamin , fetus , teratology , medicine , prostaglandin , obstetrics , endocrinology , biology , genetics
Prenatal echographical findings of a partial sirenomelic fetus are described. An attempt was made to terminate pregnancy by administration of prostaglandin F 2 a, but uterine rupture occurred. The teratogenic role of vitamin A ingested by the mother in the penconceptional period is discussed.