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Prenatal detection of the congenital nephrotic syndrome (Finnish type) by trehalase assay in amniotic fluid
Author(s) -
Morin Pierre R.,
Potier Michel,
Dallaire Louis,
Melançon Serge B.
Publication year - 1984
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1970040404
Subject(s) - amniotic fluid , trehalase , fetus , congenital nephrotic syndrome , prenatal diagnosis , nephrotic syndrome , medicine , obstetrics , andrology , pregnancy , chemistry , biology , enzyme , biochemistry , kidney , genetics , proteinuria
We report relatively high trehalase activity in the amniotic fluid of two fetuses affected with the congenital nephrotic syndrome of the Finnish type. The results suggest that prenatal detection of this condition can be done on this basis in conjunction with the α‐fetoprotein and acetylcholinesterase tests in amniotic fluid.