Premium
Prenatal diagnosis of pericentric inversion of chromosome no. 17 in a twin pregnancy
Author(s) -
Kassam Gulzar,
Chen Andrew T. L.,
Goldberg Marshall F.,
Trusler Suzanne,
Oakley Godfrey P.
Publication year - 1984
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1970040309
Subject(s) - chromosomal inversion , prenatal diagnosis , pregnancy , obstetrics , medicine , chromosome 9 , chromosome , genetics , gynecology , biology , karyotype , fetus , gene
Although prenatal genetic diagnosis can usually provide prospective parents with information as to whether their fetus is affected with certain genetic conditions, the presence of twins and the uncertainty about the phenotype of some chromosome variations pose a major dilemma and make genetic counselling very difficult. Here, a case report of an unusual chromosome aberration (pericentric inversion of chromosome no. 17) in a twin pregnancy which was originally suspected to be monoamniotic but later proved to have two sacs was presented.