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Experiences with unexpected structural chromosome aberrations in prenatal diagnosis in a danish series
Author(s) -
Vejerslev Lars O.,
Friedrich Ursula
Publication year - 1984
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1970040304
Subject(s) - danish , series (stratigraphy) , prenatal diagnosis , chromosome , genetics , medicine , karyotype , biology , obstetrics , pregnancy , fetus , gene , philosophy , linguistics , paleontology
The investigation of 5547 prenatal diagnoses showed 31 unexpected structural chromosome rearrangements. These included 3 Robertsonian translocations, 14 reciprocal translocations and 14 inversions. A11 were balanced, including 5 de novo rearrangements. In 3 of these cases an induced abortion was performed and in 2 cases children without detectable malformations were delivered.
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