Prenatal diagnosis of fragile X in a heterozygous female fetus and postnatal follow‐up | Zendy

Wilson Miriam G. | Zendy; Marchese Cristiana A. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Prenatal diagnosis of fragile X in a heterozygous female fetus and postnatal follow‐up

Author(s) -

Wilson Miriam G.,

Marchese Cristiana A.

Publication year - 1984

Publication title -

prenatal diagnosis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.956

H-Index - 97

eISSN - 1097-0223

pISSN - 0197-3851

DOI - 10.1002/pd.1970040109

Subject(s) - fragile x syndrome , fragile x , fetus , prenatal diagnosis , pregnancy , heterozygote advantage , medicine , chromosomal fragile site , obstetrics , biology , genetics , genotype , psychiatry , gene , chromosome

An apparently normal female infant was born after the prenatal diagnosis of fragile Xq27×28 present in about 4 per cent of amniocytes. The mildly retarded mother had been found in early pregnancy to be heterozygous for fragile X. The child, now 9 months old. showed about the same level of fragile X expression as her mother. Variations in the proportion of cells with fragile X appeared to be related to cell type and laboratory techniques. The infant's growth and development have been normal. Different techniques to induce or increase the expression of fragile X are discussed.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research