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Prenatal diagnosis of a double heterozygote for two reciprocal translocations of familial origin
Author(s) -
Mulcahy Marie T.,
Watson Marcia
Publication year - 1983
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1970030413
Subject(s) - heterozygote advantage , chromosomal translocation , prenatal diagnosis , reciprocal , genetics , medicine , obstetrics , pregnancy , fetus , biology , genotype , gene , philosophy , linguistics
Two balanced reciprocal translocations were found in an amniotic fluid cell culture undertaken because of maternal age. One translocation had been inherited from each parent. Both translocations were traced through three generations of each family. The importance of banding techniques in diagnostic cytogenetics is stressed.