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Prenatal diagnosis of cleft lip and palate by ultrasound
Author(s) -
Savoldelli G.,
Schmid W.,
Schinzel A.
Publication year - 1982
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1970020412
Subject(s) - medicine , trisomy , maxilla , prenatal diagnosis , fetus , ultrasonography , pregnancy , aneuploidy , ultrasound , obstetrics , prenatal ultrasound , orthodontics , radiology , chromosome , biology , genetics , biochemistry , gene
Bilateral cleft lip and cleft palate can be diagnosed by ultrasonography prior to 20 weeks of pregnancy. The anomaly produces an abnormal facial profile and, on cross‐section, the clefts in the maxilla are demonstrable. The method is illustrated by sonograms from a fetus in which the defect was diagnosed before trisomy 13 became known by karyotyping.